This function retrieves colocalisation data for a specific study locus from a GWAS study with other GWAS studies. It returns a data frame of the studies that colocalise with the input study locus, including details on the study, reported trait, index variant, and calculated colocalisation method outputs.
Value
Returns a data frame of the studies that colocalise with the input study locus. The table consists of the following data structure:
study.studyId
: Character vector. Study identifier.study.traitReported
: Character vector. Reported trait associated with the colocalisation.study.projectId
: Character vector. Project identifier for the study.study.publicationFirstAuthor
: Character vector. First author of the publication.indexVariant.id
: Character vector. Index variant identifier.indexVariant.position
: Integer vector. Index variant position.indexVariant.chromosome
: Character vector. Index variant chromosome.indexVariant.referenceAllele
: Character vector. Reference allele of the variant.indexVariant.alternateAllele
: Character vector. Alternate allele of the variant.pValueMantissa
: Numeric vector. Mantissa of the p-value for the colocalisation.pValueExponent
: Integer vector. Exponent of the p-value for the colocalisation.numberColocalisingVariants
: Integer vector. Number of colocalising variants.colocalisationMethod
: Character vector. Method used for colocalisation analysis.h3
: Numeric vector. H3 value associated with the colocalisation.h4
: Numeric vector. H4 value associated with the colocalisation.clpp
: Numeric vector. Colocalisation posterior probability.betaRatioSignAverage
: Numeric vector. Average sign of the beta ratio.